################################################################################################
# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Aug 12 21:24:01 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/MUSTANG_HOMSTRAD/results/rhv.html
################################################################################################
#====================================
# Aligned_structures: 6
# 1: 1bbt.pdb
# 2: 1r1a.pdb
# 3: 1tme.pdb
# 4: 2mev.pdb
# 5: 2plv.pdb
# 6: 4rhv.pdb
#
# Length: 1033
# Identity: 69/1033 ( 6.7%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 131/1033 ( 12.7%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 452/1033 ( 43.8%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1bbt.pdb 1 ---------------------------------------TTSAGESADPVTTTVENYG-G 20
1r1a.pdb 1 NYIDEVLNE---------VLVVP--NIKESHHTTSNSAPLLDAAETGHTSNVQPEDAIET 49
1tme.pdb 1 ---------------------------------------GSDNAEKGKVSNDDASVDFVA 21
2mev.pdb 1 ---------------------------------------GVENAEKGVTENTDATADFVA 21
2plv.pdb 1 ---------GSSSTAATSRDALP--NTEASGPTHSKEIPALTAVETGATNPLVPSDTVQT 49
4rhv.pdb 1 -----------------------TVASISSGPKHTQKVPILTANETGATMPVLPSDSIET 37
E g
1bbt.pdb 21 ETQI--QRRQHTDVSFIMDRFVKVTPQNQ-------------------------INILDL 53
1r1a.pdb 50 RYVITSQTRDEMSIESFLGRSGCVHISRIKVD--YT---D----YNG-QDINFTKWKITL 99
1tme.pdb 22 EPVK--LPENQTRVAFFYDRAVPIGMLRP-GQ--N--IESTFVYQEN-DLRL-NCLLLTP 72
2mev.pdb 22 QPVY--LPENQTKVAFFYDRSSPIGAFAV-K-S-G-SLESGFAPFSN-KACP-NSVILTP 73
2plv.pdb 50 RHVVQHRSRSESSIESFFARGACVTIMTVDNPA-ST---TNKDK-------LFAVWKITY 98
4rhv.pdb 38 RTTYMHFNGSETDVECFLGRAACVHVTEIQNKDATG---IDNHR---EA-KLFNDWKINL 90
f R
1bbt.pdb 54 MQ---------------------------VPS----------H-TLVGGLLRASTYYFSD 75
1r1a.pdb 100 QE---------------------------MA-------------Q-IRRKFELFTYVRFD 118
1tme.pdb 73 LPSFCPDSTSG-PVKTKAPVQWRWVRSGG----TTNFPLMTKQDYAFLCF-SPFTYYKCD 126
2mev.pdb 74 GPQFD------PAYDQLRPQRLTEIWGNGNEETSEVFPLKTKQDYSFCLF-SPFVYYKCD 126
2plv.pdb 99 KD---------------------------TV-------------Q-LRRKLEFFTYSRFD 117
4rhv.pdb 91 SS---------------------------LV-------------Q-LRKKLELFTYVRFD 109
ftY D
1bbt.pdb 76 LEIAVKH----------------EGDLTWVPNGAPEK----------ALD-NTTNPTAYH 108
1r1a.pdb 119 SEITLVPCIAGRGD---DI-GHIVMQYMYVPPGAPIPS-K---R-NDFSWQSGTNMSIFW 169
1tme.pdb 127 LEVTVSALG----T-----DTV-ASVLRWAPTGAPADVTDQLIGYTPSLG-ETRNPHMWL 175
2mev.pdb 127 LEVTLSPHT----S-----GAH-GLLVRWCPTGTPTKPTTQVLHEVSSLS-EGRTPQVYS 175
2plv.pdb 118 MELTFVVTANFTETNNGHA-LNQVYQIMYVPPGAPVPE-K---W-DDYTWQTSSNPSIFY 171
4rhv.pdb 110 SEYTILATASQPDSAN-YS-SNLVVQAMYVPPGAPNPK-E---W-DDYTWQSASNPSVFF 162
E t P GaP np
1bbt.pdb 109 --K--APLTRLALPYTAPHRVLATVY-NGECA-----------------TLPT-----SF 141
1r1a.pdb 170 QHG--QPFPRFSIPFLSIASAYYMFY-DGY--DGDN-------T-S---SKYGSVV-T-N 211
1tme.pdb 176 VGAG-NTQISFVVPYNSPLSVLPAAWFNGW--SDFG-------N-TKDFGVAP-----NA 219
2mev.pdb 176 AGPGTSNQISFVVPYNSPLSVLPAVWYNGH--KRFD-------N-TGDLGIAP-----NS 220
2plv.pdb 172 TYG--TAPARISVPYVGISNAYSHFY-DGF--SKVPLKDQSAALGD---SLYGAASL--N 221
4rhv.pdb 163 KV---GDTSRFSVPYVGLASAYNCFY-DGY--SHDD-------A-E---TQYGITV-L-N 203
Py G
1bbt.pdb 142 NYGAIKATRV--------------TELLYRMKRAETYCPRPLLA------------IHPT 175
1r1a.pdb 212 DMGTICSR--IVTEKQKLSV-VITTHIYHKAKHTKAWCPRPPRAVPYTHSHVTN--YMPE 266
1tme.pdb 220 DFGRLWIQ--G----------NTSASVRIRYKKMKVFCPRPTLF----------F-PWPV 256
2mev.pdb 221 DFGTLFFA--GTK-------PDIKFTVYLRYKNMRVFCPRPTVF----------F-PWPT 260
2plv.pdb 222 DFGILAVR--VVNDHNPTKV-TSKIRVYLKPKHIRVWCPRPPRAVAYYGPGV-D-YKDG- 275
4rhv.pdb 204 HMGSMAFR--IVNEHDEHKT-LVKIRVYHRAKHVEAWIPRAPRALPYTSIGRTN-YPKN- 258
G K cPRp
1bbt.pdb 176 EAR-HKQKIVAP---------LL--------EDRILTTRNGHTTSTTQSSVGVTYGYATA 217
1r1a.pdb 267 TG---DVTTAIVRRNTI-TTA----------D-RIMQITRGDSTISSDDVANAVVGYGVW 311
1tme.pdb 257 -------------------------------D-RVASDKAGNSATNTQSTVGRLCGYGEA 284
2mev.pdb 261 SGDKIDM----------------T---ENLSD-RVSQDTAGNTVTNTQSTVGRLVGYGTV 300
2plv.pdb 276 -T-----LTPLSTKD-L-TTY---EACGY-SD-RVLQLTLGNSTITTQEAANSVVAYGRW 322
4rhv.pdb 259 -T-----EPVIKKRKGDIKSY------GY-SD-RVQQITLGNSTITTQEAANAVVCYAEW 304
d R G tq Y
1bbt.pdb 218 EDFVS-G-PNTSGLETRVV-QAERFFKTHLFDWVTSDSFGRCHLLELPTDH------KGV 268
1r1a.pdb 312 PHYLTPQDATAINKPTQPDTSSNRFYTLESKHWNGSS---KGWWWKLPD--ALKD--MGI 364
1tme.pdb 285 HHGEH-P-ASCADTATDKVLAAERYYTIDLASWTTTQEAFSHIRIPLPH--VLAGEDGGV 340
2mev.pdb 301 HDGEH-P-ASCADTASEKILAVERYYTFKVNDWTSTQKPFEYIRIPLPH--VLSGEDGGV 356
2plv.pdb 323 PEYLRDSEANPVDQPTEPDVAACRFYTLDTVSWTKES---RGWWWKLPD--ALRD--MGL 375
4rhv.pdb 305 PEYLPDVDASDVNKTSKPDTSVCRFYTLDSKTWTTGS---KGWCWKLPD--ALKD--MGV 357
a R yt W LP G
1bbt.pdb 269 YGSLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELCS------------------- 309
1r1a.pdb 365 FGENMYYHFLGRSGYTVHVQCNASKFHQGTLLVAMIPEHQLA-SAK-HGSV-TAGYKL-T 420
1tme.pdb 341 FGATLRRHYLCKTGWRVQVQCNASQFHAGSLLVFMAPEFYTGKGTKTGDME-PT---D-P 395
2mev.pdb 357 FGATLRRHYLVKTGWRVQVQCNASQFHAGSLLVFMAPEYPTL----------------DV 400
2plv.pdb 376 FGQNMYYHYLGRSGYTVHVQCNASKFHQGALGVFAVPEMCLA-GDS-NTTTMHTSYQN-A 432
4rhv.pdb 358 FGQNMFFHSLGRSGYTVHVQCNATKFHSGCLLVVVIPEHQLA-SHE-GGNV-SVKYTF-T 413
fG h l G V Vqcna Fh G LlV PE
1bbt.pdb 310 -----------IQ------------------------KR--------------ELYQLTL 320
1r1a.pdb 421 HPGEAGRDVSQER---DAS-----LRQPSDDSWLNFD--------------GTLLGNLLI 458
1tme.pdb 396 FTMDT--TWRAPQ----------------GAPT----GYRYDSRTGFFAMNHQNQWQWTV 433
2mev.pdb 401 FAMDN--RWSK------------------DNLPNGTRTQT-N-RKGPFAMDHQNFWQWTL 438
2plv.pdb 433 NPGEKGGT-FTGTFTPD-NNQTSPARRFCPVDYLLG--------------NGTLLGNAFV 476
4rhv.pdb 414 HPGERGID-LS-SANE--------VGGPVKDVLYNM--------------NGTLLGNLLI 449
1bbt.pdb 321 FPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLVVMVVAPLTVNTEGAPQIKVYAN 380
1r1a.pdb 459 FPHQFINLRSNNSATLIVPYVNAVPMDSMLRHNNWCLVIIPISPLRSETTSSNIVPITVS 518
1tme.pdb 434 YPHQILNLRTNTTVDLEVPYVNIAPTSSWTQHANWTLVVAVFSPLQYASGSSSDVQITAS 493
2mev.pdb 439 YPHQFLNLRTNTTVDLEVPYVNIAPTSSWTQHASWTLVIAVVAPLTYSTGASTSLDITAS 498
2plv.pdb 477 FPHQIINLRTNNCATLVLPYVNSLSIDSMVKHNNWGIAILPLAPLNFASESSPEIPITLT 536
4rhv.pdb 450 FPHQFINLRTNNTATIVIPYINSVPIDSMTRHNNVSLMVIPIAPLTVPTGATPSLPITVT 509
PHQ NlRtN Pyvn s H w l PL it
1bbt.pdb 381 IAPTNVHVAGEFPSK----E--G-IFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNQL 433
1r1a.pdb 519 ISPMCAEFSGARAK-NIK-Q----GLPVYITPGSGQFMTTDDMQSPCALPWYHPTKEISI 572
1tme.pdb 494 IQPVNPVFNGLRHE-TVI-A--S-PIAVTVREHKGCFYSTNPDTTVPIYGKTISTPNDYM 548
2mev.pdb 499 IQPVRPVFNGLRHE-VLS--RQS-PIPVTIREHAGTWYSTLPDSTVPIYGKTPVAPANYM 554
2plv.pdb 537 IAPMCCEFNGLRNI-TLPRL---QGLPVMNTPGSNQYLTADNFQSPCALPEFDVTPPIDI 592
4rhv.pdb 510 IAPMCTEFSGIRSK-SIVPQ----GLPTTTLPGSGQFLTTDDRQSPSALPNYEPTPRIHI 564
I P f G r pv g t p
1bbt.pdb 434 PGRFTNLLDVAEACPTFLRFE--------------GGVPYVTTKTD-S-DRVLAQFDMSL 477
1r1a.pdb 573 PGEVKNLIEMCQ-VDTLIPVN---NVGNNV-GNVS--MYTVQLGNQTGMAQKVFSIKVDI 625
1tme.pdb 549 CGEFSDLLELCK-LPTFLGNPNSN-N---------KRYPYFSATNS-VPTTSLVDYQVAL 596
2mev.pdb 555 VGEYKDFLEIAQ-IPTFIGNK---VP---------NAVPYIEASNTAVKTQPLAVYQVTL 601
2plv.pdb 593 PGEVKNMMELAE-IDTMIPFD---LSATKK-NTME--MYRVRLSDKPHTDDPILCLSLSP 645
4rhv.pdb 565 PGKVHNLLEIIQ-VDTLIPMN---NTHT--KDEVN--SYLIPLNANRQN-EQVFGTNLFI 615
G e T
1bbt.pdb 478 AA-KHMSNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKARYMVAYAPPGMEPPKTPEAAA 536
1r1a.pdb 626 TS-TPLATTLIGEIASYYTHWTGSLRFSFMFCGTANTTLKLLLAYTPPGIDEPTTRKDAM 684
1tme.pdb 597 SC-SCMCNSMLAAVARNFNQYRGSLNFLFVFTGAAMVKGKFLIAYTPPGAGKPTTRDQAM 655
2mev.pdb 602 SC-SCLANTFLAALSRNFAQYRGSLVYTFVFTGTAMMKGKFLIAYTPPGAGKPTSRDQAM 660
2plv.pdb 646 ASDPRLSHTMLGEILNYYTHWAGSLKFTFLFCGSMMATGKLLVSYAPPGADPPKKRKEAM 705
4rhv.pdb 616 GD-GVFKTTLLGEIVQYYTHWSGSLRFSLMYTGPALSSAKLILAYTPPGARGPQDRREAM 674
t l Gsl f f G k aY PPG P r Am
1bbt.pdb 537 HCIHAEWDTGLNSKFTFSIPYLSAADYTYTASDVAETTNVQGWVCLFQITHG---K--A- 590
1r1a.pdb 685 LGTHVVWDVGLQSTISLVVPWVSASHFRLTADNK---YSMAGYITCWYQTN-LVVPPSTP 740
1tme.pdb 656 QATYAIWDLGLNSSFVFTAPFISPTHYRQTSYTSAA--SVDGWVTVWQLTP-LTYPSGTP 712
2mev.pdb 661 QATYAIWDLGLNSSYSFTVPFISPTHFRMVGTDQANITNVDGWVTVWQLTP-LTYPPGCP 719
2plv.pdb 706 LGTHVIWDIGLQSSCTMVVPWISNTTYRQTIDDS---FTEGGYISVFYQTR-IVVPLSTP 761
4rhv.pdb 675 LGTHVVWDIGLQSTIVMTIPWTSGVQFRYTDPDT---YTSAGFLSCWYQTS-LILPPETT 730
t WD GL S P S r t G T p
1bbt.pdb 591 DGDALVVLASAGKDFELRLPVDARAE----------------------------SGNTGS 622
1r1a.pdb 741 QTADMLCFVSACKDFCLRMARDTDLHIQSG--PIEQ---------Y-----F-------- 776
1tme.pdb 713 VNSDILTLVSAGDDFTLRMPISPT--------KWVP----------------Q-SGNEGV 747
2mev.pdb 720 TSAKILTMVSAGKDFSLKMPISPA--------PWSP----------------QSEGNEGV 755
2plv.pdb 762 REMDILGFVSACNDFSVRLLRDTTHIEQKAGAQVSSQKVGAHENSNSTINYT-------- 813
4rhv.pdb 731 GQVYLLSFISACPDFKLRLMKDTQTISQTV--ALTE------------------------ 764
l SA DF lr
1bbt.pdb 623 IINNYYMQ-QYQNSMDT--QLG--NDWFSKLASSA-----FSGLFGA-LLA--------- 662
1r1a.pdb 777 -NINYFKDAASSGASRL--D---------------------------------------- 793
1tme.pdb 748 IINNFYSN-QYQNSIDL--SAS-------------------------------------- 766
2mev.pdb 756 IINNFYSN-QYQNSIDL--SAN-------------ATGSDPPKTYGQFSN-LLSGAVNAF 798
2plv.pdb 814 -TINYYRDSASNAASKQDFS--QDPSKFTEP-----------------------IKDVLI 847
4rhv.pdb 765 --INYYKDAASTSSAGQSLS--MDPSKFTEP-----------------------VKDLML 797
N y
1bbt.pdb -------------
1r1a.pdb -------------
1tme.pdb -------------
2mev.pdb 799 SN--MLPLLA--- 806
2plv.pdb 848 --KTAP----MLN 854
4rhv.pdb 798 --KGAP----ALN 804
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
################################################EOF#################################################