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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Aug 12 21:16:37 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/MUSTANG_HOMSTRAD/results/mofe.html
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#====================================
# Aligned_structures: 6
# 1: 1mioa.pdb
# 2: 1miob.pdb
# 3: 1qh8a.pdb
# 4: 1qh8b.pdb
# 5: 3mina.pdb
# 6: 3minb.pdb
#
# Length: 682
# Identity: 24/682 ( 3.5%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 41/682 ( 6.0%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 308/682 ( 45.2%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1mioa.pdb 1 -------------------------------------------------------S---- 1
1miob.pdb 1 ---LDATPKEI--------------------------------------------VE--- 10
1qh8a.pdb 1 ---------------------------------------------------------TNA 3
1qh8b.pdb 1 SQTIDKINSC-YPLFEQDEYQELFRNKRQLEEAHDAQRVQEVFAWTTTAEYEALNFR--- 56
3mina.pdb ------------------------------------------------------------
3minb.pdb 1 -------------------------------EKYPQDKIDEVFQWTTTKEYQELNFQ--- 26
1mioa.pdb 2 -----ENLKDEILEKYIPKTKKTRSGHIVIKTEETPNP--EIVANTRTVPGIITA----- 49
1miob.pdb 11 -------------------------------------------RKALR---INPAKTCQP 24
1qh8a.pdb 4 TGERNLALIQEVLEVFPETARKERRKHMMVSDPKMKSVGKCIISNRKSQPGVMTV----- 58
1qh8b.pdb 57 -------------------------------------------REALT---VDPAKACQP 70
3mina.pdb 1 SREEVESLIQEVLEVYPEKARKDRNKHLAVN---------CIISNKKSQPGLMTI----- 46
3minb.pdb 27 -------------------------------------------REALT---VNPAKACQP 40
1mioa.pdb 50 -----------RGCAYAGCKGVVMGPIKDMVHITHG----PIGCSFYTWGGRRFKSKP-E 93
1miob.pdb 25 VGAMYAALGIH-----------------NCLPHSHGSQGCCSYHRTVLSRHFKEP----- 62
1qh8a.pdb 59 -----------RGCAYAGSKGVVFGPIKDMAHISHG----PVGCGQYSRAGRRNYYTGVS 103
1qh8b.pdb 71 LGAVLCSLGFA-----------------NTLPYVHGSQGCVAYFRTYFNRHFKEP----- 108
3mina.pdb 47 -----------RGCAYAGSKGVVWGPIKDMIHISHG----PVGCGQYSRAGRRNYYIGTT 91
3minb.pdb 41 LGAVLCALGFE-----------------KTMPYVHGSQGCVAYFRSYFNRHFREP----- 78
HG y
1mioa.pdb 94 NGTGLNFNEYVFSTDMQESDIVFGGVNKLKDAIHEAYEMFH-PAAIGVYATCPVGLIGDD 152
1miob.pdb 63 --------AMASTSSFTEGASVFGGGSNIKTAVKNIFSLYN-PDIIAVHTTCLSETLGDD 113
1qh8a.pdb 104 GV--DSFGTLNFTSDFQERDIVFGGDKKLSKLIEEMELLFPLTKGITIQSECPVGLIGDD 161
1qh8b.pdb 109 --------IACVSDSMTEDAAVFGGNNNMNLGLQNASALYK-PEIIAVSTTCMAEVIGDD 159
3mina.pdb 92 GV--NAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGLIGDD 149
3minb.pdb 79 --------VSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYK-PDMIAVSTTCMAEVIGDD 129
E VFGG I v C iGDD
1mioa.pdb 153 ILAVAATASKEIG----IPVHAFSCEGYKGVSQSAGHHIANNTVMTDII-GK--G---N- 201
1miob.pdb 114 LPTYISQMEDAGSIPEGKLVIHTNTPSYVG-SHVTGFANMVQGIVNYLS-E---N---TG 165
1qh8a.pdb 162 ISAVANASSKALD----KPVIPVRCEGFRGVSQSLGHHIANDVVRDWIL-NN--REG-QP 213
1qh8b.pdb 160 LQAFIANAKKDGFVDSSIAVPHAHTPSFIG-SHVTGWDNMFEGFAKTFTADY--Q-G-Q- 213
3mina.pdb 150 IESVSKVKGAELS----KTIVPVRCEGFRGVSQSLGHHIANDAVRDWVL-GK--RDEDTT 202
3minb.pdb 130 LNAFINNSKKEGFIPDEFPVPFAHTPSFVG-SHVTGWDNMFEGIARYFTLKSMDD-K-V- 185
v G S G
1mioa.pdb 202 K-EQKKYSINVLGEYNIGGDAWEMDRVLEKIGYHVNATLTG------------------- 241
1miob.pdb 166 A-KNGKINVIPGFVGP--ADMREIKRLFEAMDIPYIM-FPDTSGVLDGPTTGEYKMYPEG 221
1qh8a.pdb 214 F-ETTPYDVAIIGDYNIGGDAWASRILLEEMGLRVVAQWSG------------------- 253
1qh8b.pdb 214 PGKLPKLNLVTGFETY-LGNFRVLKRMMEQMAVPCSL-LSDPSEVLDTPADGHYRMYSG- 270
3mina.pdb 203 F-ASTPYDVAIIGDYNIGGDAWSSRILLEEMGLRCVAQWSG------------------- 242
3minb.pdb 186 VGSNKKINIVPGFETY-LGNFRVIKRMLSEMGVGYSL-LSDPEEVLDTPADGQFRMYAG- 242
g e m
1mioa.pdb 242 DATYEKVQNADKADLNLVQCHRSINYIAEMMETKYGIPWIKCN-FIGVDGIVETLRDMAK 300
1miob.pdb 222 GTKIEDLKDTGNSDLTLSLGSYASDLGAKTLEKKCKVPFKTLRTPIGVSATDEFIMALSE 281
1qh8a.pdb 254 DGTLVEMENTPFVKLNLVHCYRSMNYIARHMEEKHQIPWMEYN-FFGPTKIAESLRKIAD 312
1qh8b.pdb 271 GTTQQEMKEAPDAIDTLLLQPWQLLKSKKVVQEMWNQPATEVAIPLGLAATDELLMTVSQ 330
3mina.pdb 243 DGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYN-FFGPTKTIESLRAIAA 301
3minb.pdb 243 GTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSE 302
l e p G E l
1mioa.pdb 301 CFDD-P--ELTKRTEEVIAEEIAAIQDDLDYFKEKLQ--GKTACLYVGGSRSHTYMNMLK 355
1miob.pdb 282 AT-GKEVPASIEEERGQ-------LIDLMIDAQQY--LQGKKVALLGDPDEIIALSKFII 331
1qh8a.pdb 313 QF-D-D--TIRANAEAVIARYEGQMAAIIAKYRPR--LEGRKVLLYMGGLRPRHVIGAYE 366
1qh8b.pdb 331 LS-GKPIADAL----TL---ERGRLVDMMLDSHTW--LHGKKFGLYGDPDFVMGLTRFLL 380
3mina.pdb 302 KF-D-E--SIQKKCEEVIAKYKPEWEAVVAKYRPR--LEGKRVMLYIGGLRPRHVIGAYE 355
3minb.pdb 303 IS-GQPIPASL----TK---ERGRLVDMMTDSHTW--LHGKRFALWGDPDFVMGLVKFLL 352
Gk L
1mioa.pdb 356 SFGVDSLVAGFEFAHRDDYEGREVIPTIKIDADSKNIPEITVTPDEQKYRVVIPEDKVEE 415
1miob.pdb 332 ELGAIPKYVVTGTPGMK------------------------------------------- 348
1qh8a.pdb 367 DLGMEIIAAGYEFAHND------------------------------------------- 383
1qh8b.pdb 381 ELGCEPTVILSHNANKR------------------------------------------- 397
3mina.pdb 356 DLGMEVVGTGYEFAHND------------------------------------------- 372
3minb.pdb 353 ELGCEPVHILCHNGNKR------------------------------------------- 369
lG
1mioa.pdb 416 LKKAGVPLSAYG---GMMKEM-----HDGTILIDDMNHHDMEVVLEKLKPDMFFAGIKEK 467
1miob.pdb 349 ------------FQKEIDAMLAEAG-IEGSKVKVEGDFFDVHQWIKNEGVDLLISNTYGK 395
1qh8a.pdb 384 ------------DYDRTLPDL-----KEGTLLFDDASSYELEAFVKALKPDLIGSGIKEK 426
1qh8b.pdb 398 ------------WQKAMNKMLDASPYGRDSEVFINCDLWHFRSLMFTRQPDFMIGNSYGK 445
3mina.pdb 373 ------------DYDRTMKEM-----GDSTLLYDDVTGYEFEEFVKRIKPDLIGSGIKEK 415
3minb.pdb 370 ------------WKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGK 417
pD K
1mioa.pdb 468 FVIQKGG-------VLSKQLH-SY-----DYNGPYAGFRGVVNFGHELVNGIYTPAWKMI 514
1miob.pdb 396 FIAREEN-------IPFVRFGFPIMDRYGHYYNPKVGYKGAIRLVEEITNVILD--KIER 446
1qh8a.pdb 427 YIFQKMG-------VPFRQMH-SW-----DYSGPYHGYDGFAIFARDMDMTLNNPAWNEL 473
1qh8b.pdb 446 FIQRDTLAKGKAFEVPLIRLGFPLFDRHHLHRQTTWGYEGAMNIVTTLVNAVLE--KLDS 503
3mina.pdb 416 FIFQKMG-------IPFREMH-SW-----DYSGPYHGFDGFAIFARDMDMTLNNPCWKKL 462
3minb.pdb 418 FIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILE--RLDE 475
fi p G G
1mioa.pdb 515 ---TPP---WK-----KASSES 525
1miob.pdb 447 E--CTE---EDFEVVR------ 457
1qh8a.pdb 474 ---TAP---WL----------- 478
1qh8b.pdb 504 DTSQLGKTDYSFDLVR------ 519
3mina.pdb 463 ---QAP---WE----------- 467
3minb.pdb 476 ETRGMQATDYNHDLVR------ 491
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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