################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 10:48:54 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/lipase.html ################################################################################################ #==================================== # Aligned_structures: 5 # 1: 1bu8.pdb # 2: 1etha.pdb # 3: 1hpla.pdb # 4: 1lpbb.pdb # 5: 1rp1.pdb # # Length: 460 # Identity: 226/460 ( 49.1%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 314/460 ( 68.3%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 34/460 ( 7.4%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1bu8.pdb 1 KEVCYGHLGCFSNDKPWAGMLQRPLKIFPWSPEDIDTRFLLYTNENPNNYQKISATEPDT 60 1etha.pdb 1 SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVA-DPST 59 1hpla.pdb 1 NEVCYERLGCFSDDSPWAGIVERPLKILPWSPEKVNTRFLLYTNENPDNFQEIVA-DPST 59 1lpbb.pdb 1 KEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENPNNFQEVAA-DSSS 59 1rp1.pdb 1 KEVCYEQIGCFSDAEPWAGTAIRPLKVLPWSPERIGTRFLLYTNKNPNNFQTLLPSDPST 60 EVCy lGCFSdd PWaG RPLkilPWSP TRFLLYTN NpnN Q a dpst 1bu8.pdb 61 IKFSNFQLDRKTRFIVHGFIDKGEDGWLLDMCKKMFQVEKVNCICVDWRRGSRTEYTQAS 120 1etha.pdb 60 ITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQAS 119 1hpla.pdb 60 IQSSNFNTGRKTRFIIHGFIDKGEESWLSTMCQNMFKVESVNCICVDWKSGSRTAYSQAS 119 1lpbb.pdb 60 ISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCICVDWKGGSRTGYTQAS 119 1rp1.pdb 61 IGASNFQTDKKTRFIIHGFIDKGEENWLLDMCKNMFKVEEVNCICVDWKKGSQTSYTQAA 120 I SNF rKTRFIiHGFIDKGEe WL Ckn FkVE VNCICVDWk GSrT YtQAs 1bu8.pdb 121 YNTRVVGAEIAFLVQVLSTEMGYSPENVHLIGHSLGAHVVGEAGRRLEGHVGRITGLDPA 180 1etha.pdb 120 QNIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPA 179 1hpla.pdb 120 QNVRIVGAEVAYLVGVLQSSFDYSPSNVHIIGHSLGSHAAGEAGRRTNGAVGRITGLDPA 179 1lpbb.pdb 120 QNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNGTIGRITGLDPA 179 1rp1.pdb 121 NNVRVVGAQVAQMLSMLSANYSYSPSQVQLIGHSLGAHVAGEAGSRTP-GLGRITGLDPV 179 N R VGAevA v L YSPsnVh IGHSLG H aGEAGrRt gRITGLDPa 1bu8.pdb 181 EPCFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKEMPGCQ 240 1etha.pdb 180 EPCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQ 239 1hpla.pdb 180 EPCFQGTPELVRLDPSDAQFVDVIHTDIAPFIPNLGFGMSQTAGHLDFFPNGGKEMPGCQ 239 1lpbb.pdb 180 EPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGVEMPGCK 239 1rp1.pdb 180 EASFQGTPEEVRLDPTDADFVDVIHTDAAPLIPFLGFGTSQQMGHLDFFPNGGEEMPGCK 239 EpcFQGtPE VRLDPsDA FVDVIHTD AP iP LGFGmSQ GHLDFFPNGG eMPGC 1bu8.pdb 241 ------KNILSAIVDI-NGIWEGTQNFVACNHLRSYKYYASSILNPDGFLGYPCSSYEKF 293 1etha.pdb 240 KNILSQ------IVDIDGIWEG-TRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVF 292 1hpla.pdb 240 ------KNVLSQIVDI-DGIWQGTRDFAACNHLRSYKYYTDSILNPDGFAGFSCASYSDF 292 1lpbb.pdb 240 KNILSQ------IVDIDGIWEG-TRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVF 292 1rp1.pdb 240 ------KNALSQIVDL-DGIWEGTRDFVACNHLRSYKYYSESILNPDGFASYPCASYRAF 292 IVDi TrdF ACNHLRSYKYY SIlNPDGFag pC SY F 1bu8.pdb 294 QQNDCFPCPEEGCPKMGHYADQFEGKTATVE-QTVYLNTGDSGNFTRWRYKVSVTLSGAK 352 1etha.pdb 293 TANKCFPCPSEGCPQMGHYADRFPGKTNGVS-QVFYLNTGDASNFARWRYKVSVTLSGKK 351 1hpla.pdb 293 TANKCFPCSSEGCPQMGHYADRFPGRTKGVG-QLFYLNTGDASNFARWRYRVDVTLSGKK 351 1lpbb.pdb 293 TANKCFPCPSGGCPQMGHYADRYPGKTNDVG-QKFYLDTGDASNFARWRYKVSVTLSGKK 351 1rp1.pdb 293 ESNKCFPCPDQGCPQMGHYADKF--------AQKYFLNTGDSSNFARWRYGVSI-TLSGK 343 NkCFPCp GCPqMGHYAD f Q yLnTGD sNFaRWRY Vsv lsg K 1bu8.pdb 353 KLSGYILVALYGNNGNSKQYEIFKGSLKPEARHVRDIDVDINVGEIQKVKFLWNA----- 407 1etha.pdb 352 VTGHI-LVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNVI-NP 409 1hpla.pdb 352 VTGHV-LVSLFGNKGNSRQYEIFQGTLKPDNTYSNEFDSDVEVGDLEKVKFIWYNNVINL 410 1lpbb.pdb 352 VTGHI-LVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFIWYNNVINP 410 1rp1.pdb 344 RATGQAKVALFGSKGNTHQFNIFKGILKPGSTHSNEFDAKLDVGTIEKVKFLWNNN--NP 401 lV LfGn GNs QyeIfkG LkP ths efD d VG kVKF W n 1bu8.pdb 408 -APTLGASQITVQSGVDGKEYNFCSSDTVREDVLQSLYPC 446 1etha.pdb 410 TLPRVGASKITVERN-DGKVYDFCSQETVREEVLLTLNPC 448 1hpla.pdb 411 TLPKVGASKITVERN-DGSVFNFCSEETVREDVLLTLTAC 449 1lpbb.pdb 411 TLPRVGASKIIVETN-VGKQFNFCSPETVREEVLLTLTPC 449 1rp1.pdb 402 TFPKVGAAKITVQKGEEKTVHSFCSESTVREDVLLTLTPC 441 P vGAskItV g FCS TVRE VLltL pC #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################