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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sun Jul 24 02:51:42 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/ldh.html
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#====================================
# Aligned_structures: 14
# 1: 1a5z.pdb
# 2: 1bdma.pdb
# 3: 1ceqa.pdb
# 4: 1hlpa.pdb
# 5: 1ldm.pdb
# 6: 1ldna.pdb
# 7: 1llc.pdb
# 8: 1llda.pdb
# 9: 1mlda.pdb
# 10: 2cmd.pdb
# 11: 2ldx.pdb
# 12: 4mdha.pdb
# 13: 5ldh.pdb
# 14: 9ldba.pdb
#
# Length: 419
# Identity: 10/419 ( 2.4%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 15/419 ( 3.6%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 150/419 ( 35.8%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1a5z.pdb 1 -----------------------------MKIGIVGL-GRVGSSTAFALLMK--G---FA 25
1bdma.pdb 1 -------------------------MKAPVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQP 35
1ceqa.pdb 1 ---------------------------PKAKIVLVGS-GMIGGVMATLIVQK--N----L 26
1hlpa.pdb 1 -----------------------------TKVSVVGAAGTVGAAAGYNIALR--D---IA 26
1ldm.pdb 1 --AT--LKDKLI-GHL--A-TSQEPR-SYNKITVVGV-GAVGMACAISILMK--D---LA 45
1ldna.pdb 1 MK----------------------NN-GGARVVVIGA-GFVGASYVFALMNQ--G---IA 31
1llc.pdb 1 ---------------A----S-ITDK-DHQKVILVGD-GAVGSSYAFAMVLQ--G---IA 33
1llda.pdb 1 ----------------------------PTKLAVIGA-GAVGSTLAFAAAQR--G---IA 26
1mlda.pdb 1 -----------------------------AKVAVLGASGGIGQPLSLLLKNS--P---LV 26
2cmd.pdb 1 -----------------------------MKVAVLGAAGGIGQALALLLKTQ--LP--SG 27
2ldx.pdb 1 --ST--VKEQLI-QNL--V-P-EDKL-SRCKITVVGV-GDVGMACAISILLK--G---LA 44
4mdha.pdb 1 --------------------------SEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQP 34
5ldh.pdb 1 ----ATLK----EKLIAPVAQQETTI-PDNKITVVGV-GQVGMACAISILGK--S---LT 45
9ldba.pdb 1 --AT--LKDQLI-HNL----LKEEHV-PHNKITVVGV-GAVGMACAISILMK--E---LA 44
G G g
1a5z.pdb 26 REMVLIDV--DKKRAEGDALDLIHGTPFT-RR--ANIYAGD----YADLKGSDVVIVAAG 76
1bdma.pdb 36 VILQLLEIPQAMKALEGVVMELEDCA----FPLLAGLEATD-D-PDVAFKDADYALLVGA 89
1ceqa.pdb 27 GDVVLFDI--VKNMPHGKALDTSHTNVMAYSN--CKVSGSN---TYDDLAGSDVVIVTAG 79
1hlpa.pdb 27 DEVVFVDIPDKEDDTVGQAADTNHGIA--YDS--NTRVRQG---GYEDTAGSDVVVITAG 79
1ldm.pdb 46 DEVALVDV--MEDKLKGEMMDLQHGSLFL-HT--AKIVSGK---DYSVSAGSKLVVITAG 97
1ldna.pdb 32 DEIVLIDA--NESKAIGDAMDFNHGKVFA-PK--PVDIWHG---DYDDCRDADLVVICAG 83
1llc.pdb 34 QEIGIVDI--FKDKTKGDAIDLSNALPFT--S--PKKIYSA---EYSDAKDADLVVITAG 84
1llda.pdb 27 REIVLEDI--AKERVEAEVLDMQHGSSFY-PT--VSIDGSD---DPEICRDADMVVITAG 78
1mlda.pdb 27 SRLTLYDI--A--HTPGVAADLSHIE----TRA-TVKGYLGPEQLPDCLKGCDVVVIPAG 77
2cmd.pdb 28 SELSLYDI--A-PVTPGVAVDLSHIP----TAV-KIKGFSGED-ATPALEGADVVLISAG 78
2ldx.pdb 45 DELALVDA--DTDKLRGEALDLQHGSLFL-ST--PKIVFGK---DYNVSANSKLVIITAG 96
4mdha.pdb 35 IILVLLDITPMMGVLDGVLMELQDCA----LPLLKDVIATD-K-EEIAFKDLDVAILVGS 88
5ldh.pdb 46 DELALVDV--LEDKLKGEMMDLQHGSLFL-QT--PKIVANK---DYSVTANSKIVVVTAG 97
9ldba.pdb 45 DEIALVDV--MEDKLKGEMMDLQHGSLFL-RT--PKIVSGK---DYNVTANSRLVVITAG 96
d g
1a5z.pdb 77 VPQKPGETR---------LQLLGRNARVMKEIARNVSKYA-PDSIVIVVTNPVDVLTYFF 126
1bdma.pdb 90 AP-------------------LQVNGKIFTEQGRALAEVAKKDVKVLVVGNPANTNALIA 130
1ceqa.pdb 80 FT-----NRD---------DLLPLNNKIMIEIGGHIKKNC-PNAFIIVVTNPVDVMVQLL 124
1hlpa.pdb 80 IPR----QPGQ-----TRIDLAGDNAPIMEDIQSSLDEHN-DDYISLTTSNPVDLLNRHL 129
1ldm.pdb 98 ARQ----QEGE-----SRLNLVQRNVNIFKFIIPNIVKHS-PDCIILVVSNPVDVLTYVA 147
1ldna.pdb 84 ANQ----KPGE-----TRLDLVDKNIAIFRSIVESVMASG-FQGLFLVATNPVDILTYAT 133
1llc.pdb 85 A------PKQPGE---TRLDLVNKNLKILKSIVDPIVDSG-FNLIFLVAANPVDILTYAT 134
1llda.pdb 79 PRQ----KPGQ-----SRLELVGATVNILKAIMPNLVKVA-PNAIYMLITNPVDIATHVA 128
1mlda.pdb 78 VPR----KPGM-----TRDDLFNTNATIVATLTAACAQHC-PDAMICIISNPVNSTIPIT 127
2cmd.pdb 79 VRR----KPGM-----DRSDLFNVNAGIVKNLVQQVAKTC-PKACIGIITNPVNTTVAIA 128
2ldx.pdb 97 ARM----VSGQ-----TRLDLLQRNVAIMKAIVPGVIQNS-PDCKIIVVTNPVDILTYVV 146
4mdha.pdb 89 MPR----RDGMERKDL-----LKANVKIFKCQGAALDKYAKKSVKVIVVGNPANTNCLTA 139
5ldh.pdb 98 VRQ----QEGE-----SRLNLVQRNVNVFKFIIPQIVKYS-PNCIIIVVSNPVDILTYVA 147
9ldba.pdb 97 ARQ----QEGE-----SRLNLVQRNVNIFKFIIPNIVKYS-PNCKLLVVSNPVDILTYVA 146
n NP
1a5z.pdb 127 LKESG---M-DPRK-VFGSGTVLDTARLRTLIAQHCGFSPRSVH-VYVIGEHGD-SEVPV 179
1bdma.pdb 131 YKNAP---GLNPRN-FTAMT-RLDHNRAKAQLAKKTGTGVDRIRRMTVWGNHSS-IMFPD 184
1ceqa.pdb 125 HQHSG---V-PKNK-IIGLGGVLDTSRLKYYISQKLNVCPRDVN-AHIVGAHGN-KMVLL 177
1hlpa.pdb 130 YEAGD---R-SREQVIGFGG-RLDSARFRYVLSEEFDAPVQNVE-GTILGEHGD-AQVPV 182
1ldm.pdb 148 WKLSG---L-PMHR-IIGSGCNLDSARFRYLMGERLGVHSCSCH-GWVIGEHGD-SVPSV 200
1ldna.pdb 134 WKFSG---L-PHER-VIGSGTILDTARFRFLLGEYFSVAPQNVH-AYIIGEHGD-TELPV 186
1llc.pdb 135 WKLSG---F-PKNR-VVGSGTSLDTARFRQSIAEMVNVDARSVH-AYIMGEHGD-TEFPV 187
1llda.pdb 129 QKLTG---L-PENQ-IFGSGTNLDSARLRFLIAQQTGVNVKNVH-AYIAGEHGD-SEVPL 181
1mlda.pdb 128 AEVFKKHGVYNPNK-IFGVT-TLDIVRANAFVAELKGLDPARVS-VPVIGGHAGKTIIPL 184
2cmd.pdb 129 AEVLKKAGVYDKNK-LFGVT-TLDIIRSNTFVAELKGKQPGEVE-VPVIGGHSGVTILPL 185
2ldx.pdb 147 WKISG---F-PVGR-VIGSGCNLDSARFRYLIGEKLGVNPTSCH-GWVLGEHGD-SSVPI 199
4mdha.pdb 140 SKSAP---SIPKEN-FSCLT-RLDHNRAKAQIALKLGVTSDDVKNVIIWGNHSS-TQYPD 193
5ldh.pdb 148 WKLSG---L-PKHR-VIGSGCNLDSARFRYLMGEKLGVHPSSCH-GWILGEHGD-SSVAV 200
9ldba.pdb 147 WKISG---F-PKNR-VIGSGCNLDSARFRYLMGERLGVHPLSCH-GWILGEHGD-SSVPV 199
LD R G H
1a5z.pdb 180 WSGAMIG----G--I-PLQNM------C--QVCQK-C-----D-S--K---ILENFAEKT 212
1bdma.pdb 185 LFHAEVD----G--R-PALEL------V--D-----------M-E--W---YEKVFIPTV 212
1ceqa.pdb 178 KRYITVG----G--I-PLQEF------I--NNK-L-I-----S-D--A---ELEAIFDRT 209
1hlpa.pdb 183 FSKVRVD----G--T-DPE-------------------------F--SGD-EKEQLLGDL 207
1ldm.pdb 201 WSGMNVA----S--I-KLHPL------D--G-----T-NK--D--K-Q---DWKKLHKDV 231
1ldna.pdb 187 WSQAYIG----V--M-PIRKL------VESK------GEE--A-Q--K---DLERIFVNV 219
1llc.pdb 188 WSHANIG----G--V-TIAEW------V--K----AHPEI--K--E-D---KLVKMFEDV 220
1llda.pdb 182 WESATIG----G--V-PMSDWTPLPGHD--P-----L--D-------A--DKREEIHQEV 216
1mlda.pdb 185 ISQCTP-----K--V-DF------------------------P-Q--D---QLSTLTGRI 206
2cmd.pdb 186 LSQVPG--------V-SF------------------------T-E--Q---EVADLTKRI 206
2ldx.pdb 200 WSGVNVA----GVTLKSLNPA------I--------GTDK--N--K-Q---HWKNVHKQV 233
4mdha.pdb 194 VNHAKVKLQAKE--V-GVYEA------V--K-----------DDS--W---LKGEFITTV 226
5ldh.pdb 201 WSGVNVA----GV-V-LQQLN------P--E-----MGTD--N--DSE---NWKEVHKMV 234
9ldba.pdb 200 WSGVNVA----G--V-SLKNL------H--P-----E-LGTDA--DKE---HWKAVHKEV 233
1a5z.pdb 213 KRAAYEIIE-R-K--GATHYAIALAVADIVESIFFD---E--KRVLTLSVYLEDY-LGV- 261
1bdma.pdb 213 AQRGAAIIQ-ARG--ASSAASAANAAIEHIRDWALG---TPEGDWVSMAVPSQGE-YGIP 265
1ceqa.pdb 210 VNTALEIVN--LH--ASPYVAPAAAIIEMAESYLKD---L--KKVLICSTLLEGQ-YGH- 258
1hlpa.pdb 208 QESAMDVIE-R-K--GATEWGPARGVAHMVEAILHD---T--GEVLPASVKLEGE-FGH- 256
1ldm.pdb 232 VDSAYEVIK-L-K--GYTSWAIGLSVADLAETIMKN---L--CRVHPVSTMVKDF-YGI- 280
1ldna.pdb 220 RDAAYQIIE-K-K--GATYYGIAMGLARVTRAILHN---E--NAILTVSAYLDGL-YGE- 268
1llc.pdb 221 RDAAYEIIK-L-K--GATFYGIATALARISKAILND---E--NAVLPLSVYMDGQ-YGI- 269
1llda.pdb 217 KNAAYKIINGK-G--A-TNYAIGMSGVDIIEAVLHD---T--NRILPVSSMLKDF-HGI- 265
1mlda.pdb 207 QEAGTEVVK-AKAGAGSATLSMAYAGARFVFSLVDAMNGK-EGVVECSFVKSQE--TDC- 261
2cmd.pdb 207 QNAGTEVVE-AKAGGGSATLSMGQAAARFGLSLVRALQGE-QGVVECAYVEGDG--QYA- 261
2ldx.pdb 234 VEGGYEVLD-M-K--GYTSWAIGLSVTDLARSILKN---L--KRVHPVTTLVKGF-HGI- 282
4mdha.pdb 227 QQRGAAVIK-ARK--LSSAMSAAKAICDHVRDIWFG---TPEGEFVSMGIISDGNSYGVP 280
5ldh.pdb 235 VESAYEVIK-L-K--GYTNWAIGLSVADLIESMLKN---L--SRIHPVSTMVQGM-YGI- 283
9ldba.pdb 234 VDSAYEVIK-L-K--GYTSWAIGLSVADLAESIMKN---L--RRVHPISTMIKGL-YGI- 282
1a5z.pdb 262 K-DLCISVPVTLGKHGVERILE-LNLNEEELEAFRKSASILKNAINEITAEEN------ 312
1bdma.pdb 266 E-GIVYSFPVTAKDGAYRVVEG-LEINEFARKRMEITAQELLDEMEQVKALGLI----- 317
1ceqa.pdb 259 S-DIFGGTPVVLGANGVEQVIE-LQLNSEEKAKFDEAIAETKRMKALA----------- 304
1hlpa.pdb 257 E-DTAFGVPVRLGSNGVEEIVE-WDLDDYEQDLMADAAEKLSDQYDKIS---------- 303
1ldm.pdb 281 KDNVFLSLPCVLNDHGISNIVK-MKLKPNEEQQLQKSATTLWDIQKDLKF--------- 329
1ldna.pdb 269 R-DVYIGVPAVINRNGIREVIE-IELNDDEKNRFHHSAATLKSVLARAFT--------- 316
1llc.pdb 270 N-DLYIGTPAVINRNGIQNILE-IPLTDHEEESMQKSASQLKKVLTDAFAK-N----D- 320
1llda.pdb 266 S-DICMSVPTLLNRQGVNNTIN-TPVSDKELAALKRSAETLKETAAQFGF--------- 313
1mlda.pdb 262 ---PYFSTPLLLGKKGIEKNLGIGKISPFEEKMIAEAIPELKASIKKGEEFVK-N-M-- 313
2cmd.pdb 262 ---RFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGQEFVN-K---- 312
2ldx.pdb 283 KEEVFLSIPCVLGESGITDFVK-VNMTAEEEGLLKKSADTLWNMQKNLEL--------- 331
4mdha.pdb 281 D-DLLYSFPVTIKDKTWKIVEG-LPINDFSREKMDLTAKELAEEKETAFEFLS-SA--- 333
5ldh.pdb 284 ENEVFLSLPCVLNARGLTSVIN-QKLKDDEVAQLKNSADTLWGIQKDLK-D-------L 333
9ldba.pdb 283 KENVFLSVPCILGQNGISDVVK-VTLTPEEEAHLKKSADTLWGIQKELQF--------- 331
P l
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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