################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Fri Aug 12 23:28:20 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/MUSTANG_HOMSTRAD/results/igvar-h.html ################################################################################################ #==================================== # Aligned_structures: 21 # 1: 1bafhv.pdb # 2: 1bbdhv.pdb # 3: 1bvkb.pdb # 4: 1dfbhv.pdb # 5: 1faihv.pdb # 6: 1fdlhv.pdb # 7: 1hilhv.pdb # 8: 1igfhv.pdb # 9: 1igmhv.pdb # 10: 1jhlhv.pdb # 11: 1mamhv.pdb # 12: 1mcphv.pdb # 13: 1ncahv.pdb # 14: 2fb4hv.pdb # 15: 2fbjhv.pdb # 16: 3hflhv.pdb # 17: 3hfmhv.pdb # 18: 4fabhv.pdb # 19: 6fabhv.pdb # 20: 7fabhv.pdb # 21: 8fabhv.pdb # # Length: 142 # Identity: 10/142 ( 7.0%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 19/142 ( 13.4%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 33/142 ( 23.2%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1bafhv.pdb 1 DVQLQESGPGLVKPSQSQSLTCTVTGYSITSDYAWNWIRQFPGNKLEWMGYMSYS--G-S 57 1bbdhv.pdb 1 EVQLQQSGAELVRPGASVKLSCTTSGFNIK-DIYIHWVKQRPEQGLEWIGRLDPA--NGY 57 1bvkb.pdb 1 QVQLQESGPGLVRPSQTLSLTCTVSGFSLT-GYGVNWVRQPPGRGLEWIGMIWGD--G-N 56 1dfbhv.pdb 1 EVQLVESGGGLVQPGRSLRLSCAASGFTFN-DYAMHWVRQAPGKGLEWVSGISWD--SSS 57 1faihv.pdb 1 QVQLQQSGAELVRAGSSVKMSCKASGYTFT-SYGVNWVKQRPGQGLEWIGYINPG--KGY 57 1fdlhv.pdb 1 QVQLKESGPGLVAPSQSLSITCTVSGFSLT-GYGVNWVRQPPGKGLEWLGMIWGD--G-N 56 1hilhv.pdb 1 EVQLVESGGDLVKPGGSLKLSCAASGFSFS-SYGMSWVRQTPDKRLEWVATISNG--GGY 57 1igfhv.pdb 1 EVQLVESGGDLVKPGGSLKLSCAASGFTFS-RCAMSWVRQTPEKRLEWVAGISSG--GSY 57 1igmhv.pdb 1 EVHLLESGGNLVQPGGSLRLSCAASGFTFN-IFVMSWVRQAPGKGLEWVSGVFGS--GGN 57 1jhlhv.pdb 1 QVQLQQSGAELVRPGASVKLSCKASGYTFI-SYWINWVKQRPGQGLEWIGNIYPS--DSY 57 1mamhv.pdb 1 EVKLVESGGGLVQPGGSLRLSCATSGFTFT-DYYMSWVRQPPGKALEWLGFIRNKADGYT 59 1mcphv.pdb 1 EVKLVESGGGLVQPGGSLRLSCATSGFTFS-DFYMEWVRQPPGKRLEWIAASRNKGNKYT 59 1ncahv.pdb 1 QIQLVQSGPELKKPGETVKISCKASGYTFT-NYGMNWVKQAPGKGLEWMGWINTN--TGE 57 2fb4hv.pdb 1 EVQLVQSGGGVVQPGRSLRLSCSSSGFIFS-SYAMYWVRQAPGKGLEWVAIIWDD--GSD 57 2fbjhv.pdb 1 EVKLLESGGGLVQPGGSLKLSCAASGFDFS-KYWMSWVRQAPGKGLEWIGEIHPD--SGT 57 3hflhv.pdb 1 -VQLQQSGAELMKPGASVKISCKASGYTFS-DYWIEWVKQRPGHGLEWIGEILPG--SGS 56 3hfmhv.pdb 1 DVQLQESGPSLVKPSQTLSLTCSVTGDSIT-SDYWSWIRKFPGNRLEYMGYVSYS--G-S 56 4fabhv.pdb 1 EVKLDETGGGLVQPGRPMKLSCVASGFTFS-DYWMNWVRQSPEKGLEWVAQIRNKPYNYE 59 6fabhv.pdb 1 EVQLQQSGVELVRAGSSVKMSCKASGYTFT-SNGINWVKQRPGQGLEWIGYNNPG--NGY 57 7fabhv.pdb 1 AVQLEQSGPGLVRPSQTLSLTCTVSGTSFD-DYYWTWVRQPPGRGLEWIGYVFYT--G-T 56 8fabhv.pdb 1 AVKLVQAGGGVVQPGRSLRLSCIASGFTFS-NYGMHWVRQAPGKGLEWVAVIWYN--GSR 57 v L G C G W q P LEw 1bafhv.pdb 58 TRYNPSLRSRISITRDTSKNQFFLQLKSVTTEDTATYFCARG--------------W-PL 102 1bbdhv.pdb 58 TKYDPKFQGKATITVDTSSNTAYLHLSSLTSEDTAVYYCDGYYSY-Y-----------DM 105 1bvkb.pdb 57 TDYNSALKSRVTMLKDTSKNQFSLRLSSVTAADTAVYYCARERD------------Y-RL 103 1dfbhv.pdb 58 IGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDMALYYCVKGRDY-YD-SGGYF-TV-AF 113 1faihv.pdb 58 LSYNEKFKGKTTLTVDRSSSTAYMQLRSLTSEDAAVYFCARSFYG-GS-DL---AVY-YF 111 1fdlhv.pdb 57 TDYNSALKSRLSISKDNSKSQVFLKMNSLHTDDTARYYCARERD------------Y-RL 103 1hilhv.pdb 58 TYYPDSVKGRFTISRDNAKNTLYLQMSSLKSEDSAMYYCARRERY----------DE-NG 106 1igfhv.pdb 58 TFYPDTVKGRFIISRNNARNTLSLQMSSLRSEDTAIYYCTRYSSD----------PF-YF 106 1igmhv.pdb 58 TDYADAVKGRFTITRDNSKNTLYLQMNSLRAEDTAIYYCAKHRVS-Y-------VLT-GF 108 1jhlhv.pdb 58 TNYNQKFKDKATLTVDKSSSTAYMQLSSPTSEDSAVYYCTRDDNY-G-----------AM 105 1mamhv.pdb 60 TEYSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCTRDP--Y---------GP-A- 106 1mcphv.pdb 60 TEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCARNYYGS---------TW-YF 109 1ncahv.pdb 58 PTYGEEFKGRFAFSLETSASTANLQINNLKNEDKATFFCARGEDN-F-------G-S-LS 107 2fb4hv.pdb 58 QHYADSVKGRFTISRNDSKNTLFLQMDSLRPEDTGVYFCARDGGH-GFCSS-A-SCF-GP 113 2fbjhv.pdb 58 INYTPSLKDKFIISRDNAKNSLYLQMSKVRSEDTALYYCARLHY------------YGYN 105 3hflhv.pdb 57 TNYHERFKGKATFTADTSSSTAYMQLNSLTSEDSGVYYCLHGNY--------------DF 102 3hfmhv.pdb 57 TYYNPSLKSRISITRDTSKNQYYLDLNSVTTEDTATYYCANW----------------DG 100 4fabhv.pdb 60 TYYSDSVKGRFTISRDDSKSSVYLQMNNLRVEDMGIYYCTGSYY------------G-M- 105 6fabhv.pdb 58 IAYNEKFKGKTTLTVDKSSSTAYMQLRSLTSEDSAVYFCARSEYYGG--------SY-KF 108 7fabhv.pdb 57 TLLDPSLRGRVTMLVNTSKNQFSLRLSSVTAADTAVYYCARNLIA-----------G-GI 104 8fabhv.pdb 58 TYYGDSVKGRFTISRDNSKRTLYMQMNSLRTEDTAVYYCARDPDI-------L-TAF-SF 108 y D y C 1bafhv.pdb 103 AYWGQGTQVSVSEA--KTT--P 120 1bbdhv.pdb 106 DYWGPGTSVTVSSA--KTT--A 123 1bvkb.pdb 104 DYWGQGSLVTVSS--------- 116 1dfbhv.pdb 114 DIWGQGTMVTVSSA--STK--G 131 1faihv.pdb 112 DSWGQGTTLTVSSA--KTT--P 129 1fdlhv.pdb 104 DYWGQGTTLTVSSA--STT--P 121 1hilhv.pdb 107 FAYWGQGTLVTVSAA-KTT--A 125 1igfhv.pdb 107 DYWGQGTTLTVSSAK-TTP--- 124 1igmhv.pdb 109 DSWGQGTLVTVSSGSASAP-TL 129 1jhlhv.pdb 106 DYWGQGTTVTV----------- 116 1mamhv.pdb 107 AYWGQGTLVTVSAA--KTT--P 124 1mcphv.pdb 110 DVWGAGTTVTVSSE--SAR--N 127 1ncahv.pdb 108 DYWGQGTTLTVSSA--KTT--A 125 2fb4hv.pdb 114 DYWGQGTPVTVSS--------- 126 2fbjhv.pdb 106 AYWGQGTLVTVSAE--SAR--N 123 3hflhv.pdb 103 DGWGQGTTLTVSS--------- 115 3hfmhv.pdb 101 DYWGQGTLVTVSAA--KTT--P 118 4fabhv.pdb 106 DYWGQGTSVTVSSA--KTT--A 123 6fabhv.pdb 109 DYWGQGTTLTVSSA--KTT--P 126 7fabhv.pdb 105 DVWGQGSLVTVSSA--STK--G 122 8fabhv.pdb 109 DYWGQGVLVTVSSAST--KG-- 126 wg g v #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # 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