################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Fri Aug 12 22:30:57 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/MUSTANG_HOMSTRAD/results/gluts.html ################################################################################################ #==================================== # Aligned_structures: 14 # 1: 17gsa.pdb # 2: 1fhe.pdb # 3: 1glpa.pdb # 4: 1gsua.pdb # 5: 1gta.pdb # 6: 1gtua.pdb # 7: 1guha.pdb # 8: 1guka.pdb # 9: 1gula.pdb # 10: 1hna.pdb # 11: 2fhea.pdb # 12: 2gsra.pdb # 13: 3gtub.pdb # 14: 5gsta.pdb # # Length: 253 # Identity: 15/253 ( 5.9%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 19/253 ( 7.5%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 61/253 ( 24.1%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 17gsa.pdb 1 ---MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVE-----TWQ-EGSLKA--SCL 49 1fhe.pdb 1 -----PAKLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRD-----DREKWMSEKFNMGLD 50 1glpa.pdb 1 ----PPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTID-----TWM-QGLLKP--TCL 48 1gsua.pdb 1 -----VVTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLD 55 1gta.pdb 1 ----MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERD-----EGDKWRNKKFELGLE 51 1gtua.pdb 1 -----PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD 55 1guha.pdb 1 -A--EKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSA-----ED--LDKLRNDGYLM 50 1guka.pdb 1 ------PKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETR-----EQ--YEKMQKDGHLL 47 1gula.pdb 1 -----RPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETK-----EQ--LYKLQDGNHLL 48 1hna.pdb 1 -----PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD 55 2fhea.pdb 1 -----PAKLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERD-----DGEKWFSKKFELGLD 50 2gsra.pdb 1 ----PPYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTME-----TW---PPLKP--SCL 46 3gtub.pdb 1 SCE-SSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD 59 5gsta.pdb 1 -----PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLD 55 Y rG R L E 17gsa.pdb 50 YGQLPAFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIY 109 1fhe.pdb 51 LPNLPYYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCY 110 1glpa.pdb 49 YGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIY 108 1gsua.pdb 56 FPNLPYLIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCY 115 1gta.pdb 52 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAY 111 1gtua.pdb 56 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY 115 1guha.pdb 51 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPV 110 1guka.pdb 48 FGQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPF 107 1gula.pdb 49 FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPF 108 1hna.pdb 56 FPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCY 115 2fhea.pdb 51 LPNLPYYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISY 110 2gsra.pdb 47 FRQLPKFQDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIY 106 3gtub.pdb 60 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY 119 5gsta.pdb 56 FPNLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCY 115 P Q I G E D 17gsa.pdb 110 TN-YEAGKDDYVKA--------LPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLL 160 1fhe.pdb 111 NPKFEEVKEEYVKE--------LPKTLKMWSDFLG---D-RHYLTGSSVSHVDFMLYETL 158 1glpa.pdb 109 TN-YENGKNDYVKA--------LPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLL 159 1gsua.pdb 116 SPDFEKLKPAYLEQ--------LPGKLRQLSRFLG---S-RSWFVGDKLTFVDFLAYDVL 163 1gta.pdb 112 SKDFETLKVDFLSK--------LPEMLKMFEDRLC---H-KTYLNGDHVTHPDFMLYDAL 159 1gtua.pdb 116 NPEFEKLKPKYLEE--------LPEKLKLYSEFLG---K-RPWFAGNKITFVDFLVYDVL 163 1guha.pdb 111 CP-----PEEKDAKLALIKEKIKNRYFPAFEKVLKSH-G-QDYLVGNKLSRADIHLVELL 163 1guka.pdb 108 KT-----PKEKEESYDLILSRAKTRYFPVFEKILKDH-G-EAFLVGNQLSWADIQLLEAI 160 1gula.pdb 109 LK-----PDDQQKEVVNMAQKAIIRYFPVFEKILRGH-G-QSFLVGNQLSLADVILLQTI 161 1hna.pdb 116 DPDFEKLKPEYLQA--------LPEMLKLYSQFLG---K-QPWFLGDKITFVDFIAYDVL 163 2fhea.pdb 111 QPKFEQLKEGYLKD--------LPTTMKMWSDFLG---K-NPYLRGTSVSHVDFMVYEAL 158 2gsra.pdb 107 TN-YEAGKEKYVKE--------LPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLL 157 3gtub.pdb 120 SSDHEKLKPQYLEE--------LPGQLKQFSMFLG---K-FSWFAGEKLTFVDFLTYDIL 167 5gsta.pdb 116 NPDFEKQKPEFLKT--------IPEKMKLYSEFLG---K-RPWFAGDKVTYVDFLAYDIL 163 L G D 17gsa.pdb 161 LIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGN------------- 207 1fhe.pdb 159 DSIRYLAPHCLDEFPKLKEFKSRIEALPKIKAYMESKRFIKWPLNGW------------- 205 1glpa.pdb 160 LIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPINGN------------- 206 1gsua.pdb 164 DQQRMFVPDCPELQGNLSQFLQRFEALEKISAYMRSGRFMKAPIFWY------------- 210 1gta.pdb 160 DVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGW------------- 206 1gtua.pdb 164 DLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSK------------- 210 1guha.pdb 164 YYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQP-GS-PRKPPMDEKSLEEARKIFRF 221 1guka.pdb 161 LMVEELSAPVLSDFPLLQAFKTRISNIPTIKKFLQP-GS-QRKPPPDGPYVEVVRIV--- 215 1gula.pdb 162 LALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEP-GS-KKKPPPDEIYVRTVYNIF-- 217 1hna.pdb 164 ERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTK------------- 210 2fhea.pdb 159 DAIRYLEPHCLDHFPNLQQFMSRIEALPSIKAYMESNRFIKWPLNGW------------- 205 2gsra.pdb 158 RIHQVLNPSCLDAFPLLSAYVARLSARPKIKAFLASPEHVNRPINGN------------- 204 3gtub.pdb 168 DQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNK------------- 214 5gsta.pdb 164 DQYHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSK------------- 210 fp L r 17gsa.pdb 208 GKQ---------- 210 1fhe.pdb 206 AA-SFGAGDA--- 214 1glpa.pdb 207 GKQ---------- 209 1gsua.pdb 211 TA-LWNNK----- 217 1gta.pdb 207 QA-TFGGGDHPPK 218 1gtua.pdb 211 MA-VWGNK----- 217 1guha.pdb ------------- 1guka.pdb ------------- 1gula.pdb ------------- 1hna.pdb 211 MA-VFGNK----- 217 2fhea.pdb 206 HA-QFGGGDAPP- 216 2gsra.pdb 205 GKQ---------- 207 3gtub.pdb 215 MA-QWGNKPVC-- 224 5gsta.pdb 211 LA-QWSNK----- 217 #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################