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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Mon Jul 25 16:03:17 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/aadh.html
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#====================================
# Aligned_structures: 6
# 1: 1bvua.pdb
# 2: 1bw9a.pdb
# 3: 1ch6a.pdb
# 4: 1gtma.pdb
# 5: 1hrda.pdb
# 6: 1leha.pdb
#
# Length: 566
# Identity: 26/566 ( 4.6%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 59/566 ( 10.4%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 242/566 ( 42.8%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1bvua.pdb 1 --Q---------DP--------FEIAVKQ---LERAAQYMD------------------- 19
1bw9a.pdb 1 ---------------------SIDSALNW------------------------------- 8
1ch6a.pdb 1 DP----------NF--------FKMVEGF---FDRGASIVEDKLVEDLKTRQTQEQKRNR 39
1gtma.pdb 1 --A---------DP--------YEIVIKQ---LERAAQYME------------------- 19
1hrda.pdb 1 ---SKYVDRVIAEVEKKYAD--EPEFVQTVEEVLSSLGPVV--DA------------HPE 41
1leha.pdb 1 --------------------MEIFKYMEK------------------------------- 9
1bvua.pdb 20 ISE----EALEFLKRPQRIVEVSIPVEMDDGSVKVFTGFRVQYNWARGPTKGGIRWHPEE 75
1bw9a.pdb 9 --------------DGEMTVTRFDSM------TG-AHFVIRLDSTQLGPAAGGTRAAQYS 47
1ch6a.pdb 40 -VR----GILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSHQRTPCKGGIRYSTDV 94
1gtma.pdb 20 ISE----EALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQHNWARGPTKGGIRWHPEE 75
1hrda.pdb 42 ---YEEVALLERMVIPERVIEFRVPWEDDNGKVHVNTGYRVQFNGAIGPYKGGLRFAPSV 98
1leha.pdb 10 -------------YDYEQLVFCQDEA------SG-LKAVIAIHDTTLGPALGGARMWTYN 49
gP GG R
1bvua.pdb 76 ----TLSTVKALAAWMTWKTAVMDLPYGGGKGGVIC--NPKEMSDREKERLARGYVRAIY 129
1bw9a.pdb 48 NLADALTDAGKLAGAMTLKMAVSNLPMGGGKSVIALPAPRHSIDPSTWARILRIHAENID 107
1ch6a.pdb 95 ----SVDEVKALASLMTYKCAVVDVPFGGAKAGVKI--NPKNYTDEDLEKITRRFTMELA 148
1gtma.pdb 76 ----TLSTVKALAAWMTWKTAVMDLPYGGGKGGIIV--DPKKLSDREKERLARGYIRAIY 129
1hrda.pdb 99 ----NLSIMKFLGFEQAFKDSLTTLPMGGAKGGSDF--DPNGKSDREVMRFCQAFMTELY 152
1leha.pdb 50 AEEEAIEDALRLARGMTYKNAAAGLNLGGGKTVIIG--DPFADK---NEDMFRALGRFIQ 104
La mt K a lp GG K p r
1bvua.pdb 130 --DVISPYTDIPAPDVYTNPQIMAWMMDEYETISR-RKDPSFGVITGKPPSVGGIVA--- 183
1bw9a.pdb 108 --K--LSGNYWTGPDVNTNSADMDTLND-T-----------TEFVFGRSLERGGA----G 147
1ch6a.pdb 149 KKGFIGPGVDVPAPNMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHG--- 205
1gtma.pdb 130 --DVISPYEDIPAPDVYTNPQIMAWMMDEYETISR-RKTPAFGIITGKPLSIGGSLG--- 183
1hrda.pdb 153 --RHIGPDIDVPAGDLGVGAREIGYMYGQYRKIVG-G-F-YNGVLTGKARSFGGSLV--- 204
1leha.pdb 105 --G--LNGRYITAEDVGTTVDDMDLIHQ-E-----------TDYVTGISPAFG----SSG 144
a d t m tG G
1bvua.pdb 184 -RMDATARGASYTVREAAKAL-------G--MDLKGKTIAIQGYGNAGYYMAKIMSEEYG 233
1bw9a.pdb 148 SSAFTTAVGVFEAMKATVAHR-------GL-GSLDGLTVLVQGLGAVGGSLASLAAE-AG 198
1ch6a.pdb 206 -RISATGRGVFHGIENFIENASYMSILG-MTPGFGDKTFAVQGFGNVGLHSMRYLHR-FG 262
1gtma.pdb 184 -RIEATARGASYTIREAAKVL-------GW-DTLKGKTIAIQGYGNAGYYLAKIMSEDFG 234
1hrda.pdb 205 -RPEATGYGSVYYVEAVMKHE-------ND--TLVGKTVALAGFGNVAWGAAKKLAE-LG 253
1leha.pdb 145 NPSPVTAYGVYRGMKAAAKEA------FGS-DSLEGLAVSVQGLGNVAKALCKKLNT-EG 196
T G l g t qG Gn G
1bvua.pdb 234 MKVVAVSDTKGGIYNPDGL----NADEVLAWKKKT-G-SVK---DFPGATNITNEELLEL 284
1bw9a.pdb 199 AQLLVADTD-T---------------------------ERVAHAVALGHTAVALEDVLST 230
1ch6a.pdb 263 AKCVAVGESDGSIWNPDGI----DPKELEDFKLQH-G-TIL---GFPKAKIYE-GSILEV 312
1gtma.pdb 235 MKVVAVSDSKGGIYNPDGL----NADEVLKWKNEH-G-SVK---DFPGATNITNEELLEL 285
1hrda.pdb 254 AKAVTLSGPDGYIYDPEGITTEEKINYMLEMRASGRN-KVQDYADKFGVQFFPGEKPWGQ 312
1leha.pdb 197 AKLVVTDVN-K--------------------------AAVSAAVAEEGADAVAPNAIYGV 229
k v g
1bvua.pdb 285 EVDVLAPSAIEEVITKKNADNI--K-AKIVAELANGPTT-PEADEILYEKG-ILIIPDFL 339
1bw9a.pdb 231 PCDVFAPCAMGGVITTEVARTL--D-CSVVAGAANNVIADEAASDILHARG-ILYAPDFV 286
1ch6a.pdb 313 DCDILIPAASEKQLTKSNAPRV--K-AKIIAEGANGPTT-PQADKIFLERN-IMVIPDLY 367
1gtma.pdb 286 EVDVLAPAAIEEVITKKNADNI--K-AKIVAEVANGPVT-PEADEILFEKG-ILQIPDFL 340
1hrda.pdb 313 KVDIIMPCATQNDVDLEQAKKIVANNVKYYIEVANMPTT-NEALRFLMQQPNMVVAPSKA 371
1leha.pdb 230 TCDIFAPCALGAVLNDFTIPQL--K-AKVIAGSADNQLKDPRHGKYLHELG-IVYAPDYV 285
D P A a k a An a l i Pd
1bvua.pdb 340 CNAGGVTVSYFE--WVQNITGDYWTV---------------------------------- 363
1bw9a.pdb 287 ANAGGAIHLVGREVL-G------W-S---------------------------------- 304
1ch6a.pdb 368 LNAGGVTVSYFQ--ILKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPI 425
1gtma.pdb 341 CNAGGVTVSYFE--WVQNITGYYWTI---------------------------------- 364
1hrda.pdb 372 VNAGGVLVSGFE--MSQNSERLSWTA---------------------------------- 395
1leha.pdb 286 INAGGVINVADE--LYG------Y-N---------------------------------- 302
NAGGv
1bvua.pdb 364 -------------EETRAKLDKKMTKAFWDVYNTHKEKN-------INMRDAAYVVAVSR 403
1bw9a.pdb 305 -------------ESVVHERAVAIGDTLNQVFEISDNDG-------VTPDEAARTLAGRR 344
1ch6a.pdb 426 VPTAEFQDRISGA-SEKDIVHSGLAYTMERSARQIMRTAMKYNLGL-DLRTAAYVNAIEK 483
1gtma.pdb 365 -------------EEVRERLDKKMTKAFYDVYNIAKEKN-------IHMRDAAYVVAVQR 404
1hrda.pdb 396 -------------EEVDSKLHQVMTDIHDGSAAAAERYG----LG-YNLVAGANIVGFQK 437
1leha.pdb 303 -------------RTRAMKRVDGIYDSIEKIFAISKRDG-------VPSYVAADRMAEER 342
aA a
1bvua.pdb 404 VYQAMKDRGWI-------KK------ 416
1bw9a.pdb 345 AREA-ST------------------- 350
1ch6a.pdb 484 VFRVYNEAGVTFT------------- 496
1gtma.pdb 405 VYQAMLDRGWV-------KH------ 417
1hrda.pdb 438 IADAMMAQGIAW-------------- 449
1leha.pdb 343 IAKVAKARS----QFLQDQRNILNGR 364
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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