################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 06:17:24 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/Epimerase.html ################################################################################################ #==================================== # Aligned_structures: 4 # 1: 1bwsa.pdb # 2: 1bxka.pdb # 3: 1db3a.pdb # 4: 1udc.pdb # # Length: 437 # Identity: 18/437 ( 4.1%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 66/437 ( 15.1%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 174/437 ( 39.8%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1bwsa.pdb 1 KQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTR-D-----------------------E 36 1bxka.pdb 1 MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQS--E-RFAFEK 57 1db3a.pdb 1 SKVALITGVTGQDGSYLAEFLLEKG-YEVHGIKR---------------P----KFHLHY 40 1udc.pdb 1 -MRVLVTGGSGYIGSHTCVQLLQNG-HDVIILDNLCNSK-RSVLPVIE-RLGGKHPTFVE 56 litG G GS l g v 1bwsa.pdb 37 LNLLDSRAVHDFFASERIDQVYLAAAKVGGIV------ANN-TYPADFIYQNMMIESNII 89 1bxka.pdb 58 VDICDRAELARVFTEHQPDCVMHLAAESH-VDRSIDGP-------AAFIETNIVGTYTLL 109 1db3a.pdb 41 GDLSDTSNLTRILREVQPDEVYNLGA--MSHV------AVSFESPEYTADVDAMGTLRLL 92 1udc.pdb 57 GDIRNEALMTEILHDHAIDTVIHFAGLKA-VG------ESV-QKPLEYYDNNVNGTLRLI 108 d d D V aa n gt l 1bwsa.pdb 90 HAAHQND--------V-NKLLFLGSSCIYPKLAK--QPMAESELLQGTLEPTN-EPYAIA 137 1bxka.pdb 110 EAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTP----YAPS--SPYSAS 163 1db3a.pdb 93 EAIRFLG------LEKKTRFYQASTSELYGLVQE--IPQKETTP----FYPR--SPYAVA 138 1udc.pdb 109 SAMRAAN--------V-KNFIFSSSATVYGDQPK--IPYVESFP----TGTP-QSPYGKS 152 A r f s Yg p E p p sPY 1bwsa.pdb 138 KIAGIKLCESYNRQYG-RDYRSVMPTNLYGP-----HDN-----FHPSNSHVIPALLRRF 186 1bxka.pdb 164 KASSDHLVRAWLRTYG-LPTLITNCSNNYGP-----YHF-----P---E-KLIPLMILNA 208 1db3a.pdb 139 KLYAYWITVNYRESYG-MYACNGILFNHESP-----RRG-----E---T-FVTRKITRAI 183 1udc.pdb 153 KLMVEQILTDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIP---N-NLMPYIAQVA 208 K yg N gp p 1bwsa.pdb 187 HEATAQGGPDVVVWGS-----G-TPMREFLHVDDMAAASIHVMEL-A---HEVWLENTQP 236 1bxka.pdb 209 LAG----K-SLPVYGN-----G-QQIRDWLYVEDHARALYCVATTGK---V--------- 245 1db3a.pdb 184 ANIAQGLESC-LYLGN-----M-DSLRDWGHAKDYVKMQWMMLQQ-E---Q--------- 223 1udc.pdb 209 VG----RRDSLAIFGNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPG--------- 255 Gn Rd hv D a 1bwsa.pdb 237 ML-SHINVGTGVDCTIRDLAQTIAKVVG----YKG-RV--VF------------------ 270 1bxka.pdb 246 --GETYNIGGHNERKNLDVVETICELLEELAPNK-P--HGVAHY---------------- 284 1db3a.pdb 224 --PEDFVIATGVQYSVRQFVEMAAAQLG----IKL-RF--EGTGVEEKGIVVSVTGHDAP 274 1udc.pdb 256 --VHIYNLGAGVGNSVLDVVNAFSKACG----KP-VNYHFAPRR---------------- 292 n g gv d v g k 1bwsa.pdb 271 --DAS--------KPD-GT-PRKLLDVTRLHQ-LGWYHEISLEAGLASTYQWFLEN-Q-- 314 1bxka.pdb 285 ------RDLITF---------RYAIDASKIARELGCVPQETFESGMRKTVQWYLAN-ESW 328 1db3a.pdb 275 GVKPGDVIIAVDPRYFRPAEETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKH 334 1udc.pdb 293 ------E---------GDL-PAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRH-PQG 335 D k Lgw tl t w l 1bwsa.pdb ----------------- 1bxka.pdb 329 -WKQVQDGSYQGEA--- 341 1db3a.pdb 335 S---------------- 335 1udc.pdb 336 --------------YPD 338 #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################